Truncation of TGF-β docking receptor GARP is linked to human disease

TGF-β sensitivity is determined by N-linked glycosylation of the type II TGF-β receptor

N-linked glycosylation is a critical determinant of protein structure and function, regulating processes such as protein folding, stability and localization, ligand-receptor binding and intracellular signalling. TβRII [type II TGF-β (transforming growth factor β) receptor] plays a crucial role in the TGF-β signalling pathway. Although N-linked glycosylation of TβRII was first demonstrated over ...

GARP Complex on T Regulatory β TGF - 1 from the Latent β Release of Active TGF

Mediated by Integrin 1 / GARP Complex on T Regulatory β TGF - 1 from the Latent β Release of Active TGF

Integrin 1 / GARP Complex on T Regulatory β TGF - 1 from the Latent β Release of Active TGF -

GARP Complex on T Regulatory β TGF - 1 from the Latent β